The CDKN2AIP Polyclonal Antibody (CAB3233) is a valuable tool for researchers studying the CDKN2AIP protein, which is known to play a role in cell cycle regulation and tumor suppression. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds specifically to the CDKN2AIP protein, allowing for accurate detection and analysis in various cell types.CDKN2AIP, also known as CDK-interacting protein 1 (Cip1) and p21, is a key player in the regulation of cell proliferation and differentiation. Its involvement in tumor suppression pathways makes it a crucial target for research in cancer biology and therapeutics.
By understanding the activity and expression of CDKN2AIP, researchers can gain valuable insights into the mechanisms underlying cell cycle control and potential therapeutic strategies for cancer treatment.Overall, the CDKN2AIP Polyclonal Antibody is an essential tool for researchers investigating the function and regulation of the CDKN2AIP protein in various cellular processes, particularly in the context of cancer development and progression. Its high specificity and sensitivity make it a reliable choice for studies aiming to elucidate the role of CDKN2AIP in disease pathology and therapeutic interventions.
Product Name:
CDKN2AIP Rabbit Polyclonal Antibody
SKU:
CAB3233
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human CDKN2AIP (NP_060102.1).
The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55602
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CDKN2AIP antibody (CAB3233) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
