CDKN1C/p57 Kip2 Rabbit Monoclonal Antibody (CAB6843)
- SKU:
- CAB6843
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CDKN1C/p57 Kip2 Rabbit Monoclonal Antibody |
SKU: | CAB6843 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDKN1C/p57 Kip2 (P49918). |
Sequence: | MSDA SLRS TSTM ERLV ARGT FPVL VRTS ACRS LFGP VDHE ELSR ELQA RLAE LNAE DQNR WDYD FQQD MPLR GPGR LQWT EVDS DSVP AFYR ETVQ VGRC |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | BWS; WBS; p57; BWCR; KIP2; p57Kip2; CDKN1C/p57 Kip2 |
Positive Sample: | HeLa,293T,SH-SY5Y,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 32kDa |
Observed MW: | 50kDa |
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1028 |
Clone Number: | ARC1424 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |