The CDKL2 Antibody (PACO05662) is a high-quality polyclonal antibody designed for research involving CDKL2, a protein kinase implicated in cell cycle regulation and cell proliferation. This antibody, raised in rabbits, is highly specific and reactive with human, mouse, and rat samples, making it versatile for use in various research applications.CDKL2, also known as cyclin-dependent kinase-like 2, plays a crucial role in regulating cell division and growth. Dysregulation of CDKL2 has been linked to various diseases, including cancer and neurodevelopmental disorders.
By targeting CDKL2 with this antibody, researchers can visualize and study the expression and activity of CDKL2 in different cell types and tissues.The CDKL2 Antibody is validated for use in techniques such as Western blotting, immunofluorescence, and immunohistochemistry, providing researchers with a reliable tool for investigating the function of CDKL2 in biological processes. Its specificity and sensitivity make it an essential reagent for studies in cell biology, cancer research, and developmental biology.
Antibody Name:
CDKL2 Antibody (PACO05662)
Antibody SKU:
PACO05662
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human KKIAMRE.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
CDKL2: a protein kinase of the CDKL family. Accumulates primarily in the cytoplasm, with a lower level in the nucleus.Protein type: Protein kinase, CMGC; Kinase, protein; EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); Cell cycle regulation; CMGC group; CDKL familyChromosomal Location of Human Ortholog: 4q21.1Cellular Component: centrosome; nucleusMolecular Function: protein kinase activityBiological Process: sex differentiation; signal transduction
UniProt Protein Details:
NCBI Summary:
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008]
