CDKL1 Antibody (PACO01001)
- SKU:
- PACO01001
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
CDKL1 Antibody (PACO01001)
The CDKL1 Polyclonal Antibody (PACO01001) is a valuable tool for researchers studying CDKL1, a protein kinase involved in cell cycle regulation and development. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting CDKL1 in human samples, making it suitable for use in Western blot applications. By targeting the CDKL1 protein, researchers can gain insights into its functions and roles in various cellular processes.CDKL1 is known for its role in regulating cell division and differentiation, making it a promising target for cancer research and developmental biology studies.
By understanding the mechanisms of CDKL1 activity, researchers can potentially uncover new therapeutic strategies for treating cancer and other related diseases. The CDKL1 Polyclonal Antibody is a valuable tool for advancing our knowledge of this important protein and its potential implications in disease pathology.
| Antibody Name: | CDKL1 Antibody |
| Antibody SKU: | PACO01001 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Rat |
| Immunogen: | synthesized peptide derived from the C-terminal region of human KKIALRE. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | CDKL1; Cyclin-dependent kinase-like 1; Protein kinase p42 KKIALRE; Serine/threonine-protein kinase KKIALRE |
| UniProt Protein Function: | CDKL1: a protein kinase of the CDKL family. Accumulates primarily in the nucleus. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Kinase, protein; EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; CMGC group; CDKL family Chromosomal Location of Human Ortholog: 14q21.3 Cellular Component: cytoplasm; nucleus Molecular Function:cyclin-dependent protein kinase activity; ATP binding Biological Process: regulation of cell cycle; heart development; protein amino acid phosphorylation |
| NCBI Summary: | This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013] |
| UniProt Code: | Q00532 |
| NCBI GenInfo Identifier: | 229463050 |
| NCBI Gene ID: | 8814 |
| NCBI Accession: | Q00532.5 |
| UniProt Secondary Accession: | Q00532,Q2M3A4, Q6QUA0, Q8WXQ5, |
| UniProt Related Accession: | Q00532 |
| Molecular Weight: | 108,931 Da |
| NCBI Full Name: | Cyclin-dependent kinase-like 1 |
| NCBI Synonym Full Names: | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| NCBI Official Symbol: | CDKL1Â Â |
| NCBI Official Synonym Symbols: | P42; KKIALREÂ Â |
| NCBI Protein Information: | cyclin-dependent kinase-like 1; CDC2-related kinase 1; protein kinase p42 KKIALRE; serine/threonine protein kinase KKIALRE; serine/threonine-protein kinase KKIALRE |
| UniProt Protein Name: | Cyclin-dependent kinase-like 1 |
| UniProt Synonym Protein Names: | Protein kinase p42 KKIALRE; Serine/threonine-protein kinase KKIALRE |
| Protein Family: | Cyclin-dependent kinase |
| UniProt Gene Name: | CDKL1Â Â |
| UniProt Entry Name: | CDKL1_HUMAN |
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