CDK9 Rabbit Monoclonal Antibody (CAB11145)
- SKU:
- CAB11145
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | CDK9 Rabbit Monoclonal Antibody |
SKU: | CAB11145 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 273-372 of human CDK9 (P50750). |
Sequence: | RKVK DRLK AYVR DPYA LDLI DKLL VLDP AQRI DSDD ALNH DFFW SDPM PSDL KGML STHL TSMF EYLA PPRR KGSQ ITQQ STNQ SRNP ATTN QTEF ERVF |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | TAK; C-2k; CTK1; CDC2L4; PITALRE; K9 |
Positive Sample: | HeLa, 293T ,MCF7, Mouse brain, Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, PML body. |
Calculated MW: | 43kDa |
Observed MW: | 42kDa/55kDa |
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
Purification Method: | Affinity purification |
Gene ID: | 1025 |
Clone Number: | ARC0527 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |