CDK8 Rabbit Monoclonal Antibody (CAB9654)
- SKU:
- CAB9654
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | CDK8 Rabbit Monoclonal Antibody |
SKU: | CAB9654 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDK8 (P49336). |
Sequence: | MDYD FKVK LSSE RERV EDLF EYEG CKVG RGTY GHVY KAKR KDGK DDKD YALK QIEG TGIS MSAC REIA LLRE LKHP NVIS LQKV FLSH ADRK VWLL FDYA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | K35; IDDHBA; CDK8 |
Positive Sample: | Mouse brain,Rat liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus |
Calculated MW: | 53kDa |
Observed MW: | 55kDa |
This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1024 |
Clone Number: | ARC1682 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |