The CDK7 Polyclonal Antibody (CAB1694) is a valuable tool for research involving CDK7, a key regulator of the cell cycle and transcription. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is optimized for use in Western blot applications. By binding specifically to the CDK7 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in molecular biology, cancer research, and drug development.CDK7, a cyclin-dependent kinase, plays a crucial role in the regulation of cell division and gene transcription by phosphorylating key targets. Its dysregulation has been implicated in various diseases, including cancer, making it an attractive target for therapeutic intervention.
Research into the function and regulation of CDK7 is essential for developing novel treatments targeting cell growth and proliferation in cancer and other disorders.In conclusion, the CDK7 Polyclonal Antibody (CAB1694) offers researchers a reliable tool for investigating the role of CDK7 in cellular processes and disease pathology. Its high specificity and sensitivity make it a valuable resource for advancing our understanding of molecular mechanisms and identifying potential therapeutic targets in cancer and other conditions.
Product Name:
CDK7 Rabbit Polyclonal Antibody
SKU:
CAB1694
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-346 of human CDK7 (NP_001790.1).
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Purification Method:
Affinity purification
Gene ID:
1022
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse heart, using CDK7 Rabbit pAb (CAB1694) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
