CDK7 Rabbit Polyclonal Antibody (CAB1694)
- SKU:
- CAB1694
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CDK7 Rabbit Polyclonal Antibody |
SKU: | CAB1694 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-346 of human CDK7 (NP_001790.1). |
Sequence: | MALD VKSR AKRY EKLD FLGE GQFA TVYK ARDK NTNQ IVAI KKIK LGHR SEAK DGIN RTAL REIK LLQE LSHP NIIG LLDA FGHK SNIS LVFD FMET DLEV IIKD NSLV LTPS HIKA YMLM TLQG LEYL HQHW ILHR DLKP NNLL LDEN GVLK LADF GLAK SFGS PNRA YTHQ VVTR WYRA PELL FGAR MYGV GVDM WAVG CILA ELLL RVPF LPGD SDLD QLTR IFET LGTP TEEQ WPDM CSLP DYVT FKSF PGIP LHHI FSAA GDDL LDLI QGLF LFNP CARI TATQ ALKM KYFS NRPG PTPG CQLP RPNC PVET LKEQ SNPA LAIK RKRT EALE QGGL PKKL IF |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CAK; CAK1; HCAK; MO15; STK1; CDKN7; p39MO15; CDK7 |
Positive Sample: | Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, perinuclear region. |
Calculated MW: | 39kDa |
Observed MW: | 43kDa |
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Purification Method: | Affinity purification |
Gene ID: | 1022 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |