The CDK5RAP3 Polyclonal Antibody (CAB5000) is a valuable tool for researchers studying the protein CDK5RAP3, a key regulator of cell cycle progression and microtubule organization. This antibody, produced in rabbits, exhibits high specificity in detecting CDK5RAP3 in human samples and is validated for use in Western blot applications. By binding to CDK5RAP3, this antibody allows for accurate detection and analysis of the protein in a variety of cell types, making it an essential component for studies in cell biology and cancer research.CDK5RAP3, also known as C53, plays a critical role in cell division and DNA damage response pathways, making it a potential target for cancer therapy and understanding the mechanisms of tumorigenesis.
By studying the function and regulation of CDK5RAP3, researchers can gain insights into the underlying molecular processes that drive cancer growth and progression. Additionally, CDK5RAP3 has been implicated in neurodegenerative diseases, suggesting its involvement in diverse biological pathways beyond cell cycle control.In conclusion, the CDK5RAP3 Polyclonal Antibody is a valuable tool for researchers investigating the role of CDK5RAP3 in cell biology, cancer research, and neurodegenerative disorders. Its high specificity and versatility make it an ideal choice for studies aiming to unravel the complex functions of this important protein in various biological contexts.
Product Name:
CDK5RAP3 Rabbit Polyclonal Antibody
SKU:
CAB5000
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CDK5RAP3 (NP_788276.1).
This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms.
Purification Method:
Affinity purification
Gene ID:
80279
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDK5RAP3 Rabbit pAb (CAB5000) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
