The CDK5RAP3 Polyclonal Antibody (CAB13128) is a valuable tool for research involving CDK5RAP3, a protein known to play a crucial role in cell cycle regulation and microtubule organization. This antibody, raised in rabbits, specifically binds to the CDK5RAP3 protein and is highly reactive with human samples. Validated for use in Western blot applications, this antibody enables the detection and analysis of CDK5RAP3 in various cell types, making it ideal for studies in cell biology and cancer research.
CDK5RAP3 is a key player in promoting proper cell division and maintaining genomic stability. Dysregulation of CDK5RAP3 has been linked to abnormal cell growth and proliferation, making it a potential target for therapeutic interventions in cancer treatment. By understanding the role of CDK5RAP3 in cell cycle progression, researchers can provide valuable insights into potential mechanisms for controlling cell proliferation, ultimately leading to the development of new cancer therapies.
Product Name:
CDK5RAP3 Rabbit Polyclonal Antibody
SKU:
CAB13128
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CDK5RAP3 (NP_788276.1).
This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms.
Purification Method:
Affinity purification
Gene ID:
80279
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDK5RAP3 Rabbit pAb (CAB13128) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
