The CDK5RAP2 Polyclonal Antibody (CAB15476) is a valuable tool for researchers studying CDK5RAP2, a protein involved in various cellular processes, including cell cycle regulation and centrosome duplication. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CDK5RAP2 protein, this antibody allows for detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and cancer research.CDK5RAP2, also known as CDK5 regulatory subunit-associated protein 2, is essential for proper cell division and organization.
Dysregulation of CDK5RAP2 has been implicated in cancer progression and other diseases characterized by uncontrolled cell growth. Therefore, studying the function of CDK5RAP2 is crucial for identifying potential therapeutic targets and developing treatments for these conditions.Overall, the CDK5RAP2 Polyclonal Antibody (CAB15476) provides researchers with a powerful tool to explore the role of CDK5RAP2 in cellular processes and disease development, offering new insights into potential therapeutic strategies.
Product Name:
CDK5RAP2 Rabbit Polyclonal Antibody
SKU:
CAB15476
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1744-1893 of human CDK5RAP2 (NP_060719.4).
This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55755
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDK5RAP2 Rabbit pAb (CAB15476) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
