The CDK5RAP1 Polyclonal Antibody (CAB15844) is a valuable tool for researchers studying CDK5RAP1, a protein involved in cell cycle regulation and microtubule organization. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it reliable for use in Western blot assays.CDK5RAP1 is known to play a crucial role in centrosome duplication and cell division, making it a promising target for cancer research and drug development. By binding to CDK5RAP1, this antibody facilitates the detection and analysis of the protein in various cell types, enabling a deeper understanding of its function and potential therapeutic applications.
Additionally, CDK5RAP1 has been implicated in neurodevelopmental disorders and neurodegenerative diseases, highlighting its importance in the field of neuroscience and cell biology. Research utilizing the CDK5RAP1 Polyclonal Antibody can provide valuable insights into the molecular mechanisms underlying these conditions, paving the way for novel treatment strategies.
Product Name:
CDK5RAP1 Rabbit Polyclonal Antibody
SKU:
CAB15844
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human CDK5RAP1 (NP_057492.2).
This gene encodes a regulator of cyclin-dependent kinase 5 activity. This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity. Alternative splicing results in multiple transcript variants that encode different isoforms.
Purification Method:
Affinity purification
Gene ID:
51654
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDK5RAP1 Rabbit pAb (CAB15844) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
