The CDK5R2 Polyclonal Antibody (CAB17583) is a valuable tool for researchers studying CDK5R2, a protein involved in cell cycle regulation and neuronal development. This rabbit polyclonal antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CDK5R2 protein, this antibody enables the detection and analysis of CDK5R2 in various cell types, making it an essential reagent for studies in neuroscience and cancer research.CDK5R2, also known as cyclin-dependent kinase 5 regulatory subunit 2, plays a crucial role in controlling cell division and differentiation, making it a promising target for understanding the mechanisms underlying neurodevelopmental disorders and tumorigenesis.
Research on CDK5R2 may provide insights into potential therapeutic strategies for conditions such as Alzheimer's disease, Parkinson's disease, and various types of cancer. By elucidating the function of CDK5R2, researchers can uncover new avenues for drug development and personalized medicine approaches.
Product Name:
CDK5R2 Rabbit Polyclonal Antibody
SKU:
CAB17583
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-310 of human CDK5R2 (NP_003927.1).
The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins.
Purification Method:
Affinity purification
Gene ID:
8941
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using CDK5R2 Rabbit pAb (CAB17583) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
