CDK5 Polyclonal Antibody (CAB2689)
- SKU:
- CAB2689
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | CDK5 Polyclonal Antibody |
SKU: | CAB2689 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human CDK5 (NP_004926.1). |
Sequence: | MQKY EKLE KIGE GTYG TVFK AKNR ETHE IVAL KRVR LDDD DEGV PSSA LREI CLLK ELKH KNIV RLHD VLHS DKKL TLVF EFCD QDLK KYFD SCNG DLDP EIVK SFLF QLLK GLGF CHSR NVLH RDLK PQNL LINR NGEL KLAD FGLA RAFG IPVR CYSA EVVT LWYR PPDV LFGA KLYS TSID MWSA GCIF AELA NAGR PLFP GNDV DDQL KRIF RLLG TPTE EQWP SMTK LPDY KPYP MYPA TTSL VNVV PKLN ATGR DLLQ NLLK CNPV QRIS AEEA LQHP YFSD FCPP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LIS7; PSSALRE; CDK5 |
Positive Sample: | Jurkat,NIH/3T3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Cytoplasm, Nucleus, Perikaryon, Peripheral membrane protein, growth cone, lamellipodium, postsynaptic cell membrane, postsynaptic density, synapse. |
Calculated MW: | 33kDa |
Observed MW: | 33kDa |
This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1020 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |