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CDK4 Monoclonal Antibody [P6D10AT] (CPAB0170)

SKU:
CPAB0170
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
P6D10AT
€149
Frequently bought together:

Description

system_update_alt Datasheet
Product Name:CDK4 Antibody
Product Sku:CPAB0170
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CDK4 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CDK4 amino acids 1-33 purified from Ecoli.
Clone:P6D10AT.
Reactivity:Human
Applications:
Purification Method:CDK4 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:Cyclin-dependent kinase 4 combines with the protein cyclin D to form a protein complex that promotes the passage of cells through the G1 checkpoint in the cell growth cycle. This cellular activity is regulated by the protein p16 produced by p16INK4a. Normally, p16 controls cell growth by inhibiting the activity of the CDK4€“cyclin D complex and stopping cells at the G1 checkpoint.
Synonyms:Cell division protein kinase 4, CDK4, EC 2.7.11.22, Cyclin-dependent kinase 4, PSK-J3, CMM3, CDK-4, MGC14458.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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