The CDK2 Rabbit Monoclonal Antibody is a crucial tool for researchers studying the CDK2 protein, a key regulator of the cell cycle. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting CDK2 in human samples, making it ideal for use in Western blotting and immunofluorescence applications.CDK2, a member of the cyclin-dependent kinase family, plays a pivotal role in cell division and proliferation. Dysregulation of CDK2 activity is associated with various diseases, including cancer, making it a promising target for therapeutic interventions.
By targeting CDK2 with this monoclonal antibody, researchers can gain valuable insights into the protein's function and its potential as a target for anti-cancer therapies.Overall, the CDK2 Rabbit Monoclonal Antibody is a valuable tool for researchers in the fields of cell biology, oncology, and drug discovery, enabling precise and reliable detection of CDK2 to advance our understanding of cell cycle regulation and cancer biology.
Product Name:
CDK2 Rabbit Monoclonal Antibody
SKU:
CAB0094
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 199-298 of human CDK2 (P24941).
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1017
Clone Number:
ARC0222
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CDK2 Rabbit mAb (CAB0094) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
