The CDK2 Polyclonal Antibody (CAB16885) is a valuable tool for researchers studying CDK2, a critical protein involved in cell cycle regulation and cell division. This antibody, generated in rabbits, has been validated for use in Western blotting, immunofluorescence, and immunohistochemistry applications with human samples.CDK2, also known as cyclin-dependent kinase 2, plays a key role in the progression of the cell cycle and is a target for cancer therapy research. By targeting CDK2, researchers can explore the mechanisms of cell growth and proliferation, as well as potential therapeutic strategies for cancer treatment.
The CDK2 Polyclonal Antibody specifically binds to the CDK2 protein, allowing for accurate detection and analysis in various cell types. Its high reactivity and specificity make it an ideal choice for studies in cancer research, cell biology, and drug development.Overall, the CDK2 Polyclonal Antibody (CAB16885) is a valuable tool for researchers seeking to understand the role of CDK2 in cell cycle regulation and cancer development, offering reliable and reproducible results for their experiments.
Product Name:
CDK2 Rabbit Polyclonal Antibody
SKU:
CAB16885
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-298 of human CDK2 (NP_001789.2).
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1017
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDK2 Rabbit pAb (CAB16885) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
