The CDK2 Polyclonal Antibody (CAB0294) is a valuable tool for researchers studying cyclin-dependent kinase 2 (CDK2), a key regulator of cell cycle progression and a potential target for cancer therapy. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for applications such as Western blot and immunohistochemistry.CDK2 is a critical enzyme involved in the regulation of cell division and proliferation, making it a target of interest in cancer research. By targeting CDK2 with this polyclonal antibody, researchers can accurately detect and analyze the expression levels of CDK2 in various cell types and tissues, providing valuable insights into the role of CDK2 in cancer development and progression.
Furthermore, the CDK2 Polyclonal Antibody is validated for use in a variety of experimental techniques, allowing for flexibility in research applications. Its high specificity and sensitivity make it a reliable tool for scientists studying the molecular mechanisms of cancer and exploring potential therapeutic targets within the CDK2 pathway.
Product Name:
CDK2 Rabbit Polyclonal Antibody
SKU:
CAB0294
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-298 of human CDK2 (NP_001789.2).
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1017
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using [KO Validated] CDK2 Rabbit pAb (CAB0294) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
