The CDK19 Polyclonal Antibody (CAB16109) is a valuable tool for researchers studying CDK19, a cyclin-dependent kinase involved in transcription regulation and cell cycle progression. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it ideal for use in Western blot applications. By targeting the CDK19 protein, this antibody allows for precise detection and analysis in various cell types, facilitating research in fields such as molecular biology and cancer biology.CDK19 is a key player in the regulation of gene transcription and cell division, making it a potential target for therapeutic interventions in diseases like cancer, where cell cycle dysregulation is often observed.
By studying the function of CDK19, researchers can gain insights into the mechanisms driving tumorigenesis and develop targeted therapies to treat cancer and other diseases associated with abnormal cell growth. The CDK19 Polyclonal Antibody is an essential tool for unlocking the potential of CDK19 as a therapeutic target in various research settings.
Product Name:
CDK19 Rabbit Polyclonal Antibody
SKU:
CAB16109
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CDK19 (XP_005266928.1).
cytosol, nucleoplasm, nucleus, perinuclear region of cytoplasm
Calculated MW:
57kDa
Observed MW:
57kDa
This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
23097
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from DU145 cells, using CDK19 Rabbit pAb (CAB16109) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
