The CDK14 Polyclonal Antibody (CAB14986) is a powerful tool for researchers studying CDK14, a protein kinase involved in cell cycle regulation and cancer development. This antibody is produced in rabbits and has high specificity for human samples, making it an ideal choice for Western blotting experiments. By binding specifically to CDK14, this antibody allows for precise detection and analysis of the protein in various cell types.CDK14, also known as PFTAIRE1, plays a crucial role in cell division and growth, making it a potential target for cancer therapy. Overexpression of CDK14 has been linked to tumor progression and poor prognosis in various cancers, making it a promising target for drug development.
Understanding the function and regulation of CDK14 is essential for developing targeted therapies that can effectively inhibit its activity in cancer cells.Overall, the CDK14 Polyclonal Antibody (CAB14986) is a valuable tool for researchers studying cell cycle regulation, cancer biology, and drug discovery. Its high specificity and sensitivity make it a reliable choice for experiments aimed at elucidating the role of CDK14 in cancer development and progression.
Product Name:
CDK14 Rabbit Polyclonal Antibody
SKU:
CAB14986
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 312-451 of human CDK14 (NP_036527.1).
Enables cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Involved in G2/M transition of mitotic cell cycle and regulation of canonical Wnt signaling pathway. Located in cytosol; nucleoplasm; and plasma membrane. Part of cytoplasmic cyclin-dependent protein kinase holoenzyme complex.
Purification Method:
Affinity purification
Gene ID:
5218
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse testis, using CDK14 Rabbit pAb (CAB14986) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
