The CDK12 Monoclonal Antibody (CAB22474) is a valuable tool for researchers studying CDK12, a crucial protein involved in cellular processes such as transcription regulation and DNA repair. This antibody, produced using advanced monoclonal technology, is highly specific to CDK12 and exhibits minimal cross-reactivity with other proteins.CDK12 is known to play a key role in regulating gene expression and maintaining genomic integrity, making it a significant target for cancer research. Dysregulation of CDK12 has been linked to various types of cancer, underscoring the importance of studying its function and activity.With its high sensitivity and specificity, the CDK12 Monoclonal Antibody is ideal for applications such as Western blot and immunohistochemistry.
Its ability to accurately detect and quantify CDK12 protein levels in various sample types makes it a valuable tool for investigating the role of CDK12 in cancer development and progression.By using the CDK12 Monoclonal Antibody, researchers can gain valuable insights into the mechanisms underlying cancer pathogenesis and potentially identify new therapeutic targets for combating this deadly disease. Its reliability and precision make it a valuable asset for any laboratory conducting research in the field of oncology.
Product Name:
CDK12 Monoclonal Antibody
SKU:
CAB22474
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 420-516 of human CDK12 (NP_057591.2).
Enables RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in phosphorylation of RNA polymerase II C-terminal domain; protein autophosphorylation; and regulation of MAP kinase activity. Located in nuclear speck. Part of cyclin K-CDK12 complex.
Purification Method:
Affinity purification
Gene ID:
51755
Clone Number:
ARC53277
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Human heart using CDK12 Rabbit mAb (CAB22474) at dilution of 1:500 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
