null

CDK12 Monoclonal Antibody (CAB22474)

SKU:
CAB22474
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IHC
€139 - €529
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CDK12 Monoclonal Antibody
SKU:CAB22474
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 420-516 of human CDK12 (NP_057591.2).
Sequence:SKGS PVFL PRKE NSSV EAKD SGLE SKKL PRSV KLEK SAPD TELV NVTH LNTE VKNS SDTG KVKL DENS EKHL VKDL KAQG TRDS KPIA LKEE IVTP K
Tested Applications:IHC-P ELISA
Recommended Dilution:IHC-P,1:100 - 1:500
Synonyms:CRK7; CRKR; CRKRS; CDK12
Conjugate:Unconjugated
Cellular Localization:Nucleus, Nucleus speckle.
Calculated MW:164kDa
Observed MW:Refer to figures

Enables RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in phosphorylation of RNA polymerase II C-terminal domain; protein autophosphorylation; and regulation of MAP kinase activity. Located in nuclear speck. Part of cyclin K-CDK12 complex.

Purification Method:Affinity purification
Gene ID:51755
Clone Number:ARC53277
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human heart using CDK12 Rabbit mAb (CAB22474) at dilution of 1:500 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Related Products