The CDK11B Polyclonal Antibody (CAB14715) is a valuable tool for researchers studying CDK11B, a key regulator of cell cycle progression and transcription. This antibody is produced using rabbits and exhibits high reactivity with human samples, making it suitable for Western blot applications. By binding specifically to the CDK11B protein, this antibody allows for precise detection and analysis in various cell types.CDK11B plays a critical role in cell division and gene expression, making it a crucial target for studies in cancer research and developmental biology.
Understanding the function of CDK11B is essential for unraveling its contributions to cellular processes and diseases such as cancer. This antibody provides researchers with a reliable tool for investigating the mechanisms underlying CDK11B activity, paving the way for new insights into cell cycle regulation and potential therapeutic interventions.
Product Name:
CDK11B Rabbit Polyclonal Antibody
SKU:
CAB14715
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human CDK11B (NP_277021.2).
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
984
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using CDK11B Rabbit pAb (CAB14715) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
