The CDK11B Polyclonal Antibody (CAB12830) is a valuable tool for researchers studying CDK11B, a protein kinase involved in cell cycle regulation and RNA processing. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blot applications.CDK11B is known to play a crucial role in various cellular processes, including cell division, RNA splicing, and DNA damage repair. Dysregulation of CDK11B has been linked to diseases such as cancer, making it a promising target for therapeutic development.
The CDK11B Polyclonal Antibody enables researchers to detect and analyze the expression of CDK11B in different cell types, providing valuable insights into its function and potential as a therapeutic target.By using this antibody, researchers can further explore the role of CDK11B in cell biology and disease progression, ultimately contributing to the development of novel treatments for cancer and other related disorders. Its versatility and specificity make it an essential tool for studies in molecular biology and drug discovery.
Product Name:
CDK11B Rabbit Polyclonal Antibody
SKU:
CAB12830
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human CDK11B (NP_277021.2).
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
984
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDK11B Rabbit pAb (CAB12830) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
