The CDK10 Polyclonal Antibody (CAB2690) is a valuable tool for researchers studying CDK10, a cyclin-dependent kinase known for its role in cell cycle regulation and gene expression. This rabbit-raised antibody is specially designed for use in Western blot applications and is highly reactive with human samples.CDK10, a member of the CDK family, plays a crucial role in controlling cell division and gene transcription processes. Its dysregulation has been linked to various diseases, including cancer. By targeting the CDK10 protein, researchers can effectively study its function and regulation in different cell types, providing important insights into its potential roles in disease development and treatment.
The CDK10 Polyclonal Antibody is a reliable tool for immunology and cancer research, allowing for the detection and analysis of CDK10 expression in various experimental settings. By utilizing this antibody, researchers can uncover new mechanisms underlying cellular processes and potentially identify novel therapeutic targets for the treatment of cancer and other diseases.
Product Name:
CDK10 Rabbit Polyclonal Antibody
SKU:
CAB2690
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human CDK10 (NP_001092003.2).
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8558
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CDK10 antibody (CAB2690) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
