The CDIP1 Polyclonal Antibody (CAB14883) is specifically designed for research involving CDIP1, a protein involved in cell death pathways. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the CDIP1 protein, this antibody enables detection and analysis in a variety of cell types, making it an excellent tool for studying cell death mechanisms in both normal and disease settings.CDIP1, also known as cell death-inducing protein 1, plays a crucial role in regulating apoptosis, the programmed cell death process essential for normal development and tissue homeostasis.
Dysregulation of apoptosis is implicated in various diseases, including cancer and neurodegenerative disorders, highlighting the importance of studying proteins like CDIP1. By investigating the function of CDIP1, researchers can gain insights into the molecular mechanisms underlying cell death and potentially identify new therapeutic targets for treating diseases characterized by abnormal cell death processes.
Product Name:
CDIP1 Rabbit Polyclonal Antibody
SKU:
CAB14883
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CDIP1 (NP_001185983.1).
Predicted to enable metal ion binding activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and tumor necrosis factor-mediated signaling pathway. Located in cytoplasmic side of late endosome membrane; cytoplasmic side of lysosomal membrane; and nucleus.
Purification Method:
Affinity purification
Gene ID:
29965
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDIP1 Rabbit pAb (CAB14883) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.