The CDHR1 Polyclonal Antibody (CAB17808) is specifically designed for research related to CDHR1, a cell adhesion molecule known to play a role in maintaining epithelial barrier integrity and cell-cell adhesion. This rabbit-derived antibody is highly reactive with human samples and has been validated for use in various applications, including Western blotting.CDHR1, also referred to as Cadherin-23, is crucial for the function of epithelial cells, particularly in the respiratory and gastrointestinal tracts. Dysregulation of CDHR1 has been linked to a variety of diseases, including respiratory infections and inflammatory conditions. This antibody binds to the CDHR1 protein, enabling researchers to detect and analyze its expression in different cell types, thus making it an invaluable tool for studies in cell biology, epithelial cell function, and respiratory diseases.
By understanding the role of CDHR1 in maintaining epithelial barrier function, researchers can uncover potential therapeutic targets for diseases that involve epithelial dysregulation, such as asthma, COPD, and inflammatory bowel diseases. The CDHR1 Polyclonal Antibody offers researchers a reliable and specific tool for investigating the function and expression of CDHR1 in various biological contexts.
Product Name:
CDHR1 Rabbit Polyclonal Antibody
SKU:
CAB17808
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human CDHR1 (NP_001165442.1).
This gene belongs to the cadherin superfamily of calcium-dependent cell adhesion molecules. The encoded protein is a photoreceptor-specific cadherin that plays a role in outer segment disc morphogenesis. Mutations in this gene are associated with inherited retinal dystrophies. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
92211
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDHR1 Rabbit pAb (CAB17808) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
