The CDH9 Polyclonal Antibody (CAB14716) is a high-quality antibody designed for research involving CDH9, a cell adhesion molecule involved in neuronal development and synaptic plasticity. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in various applications including Western blot, immunofluorescence, and immunohistochemistry.CDH9, also known as cadherin-9, plays a crucial role in neural cell adhesion and communication, making it a key player in the formation and maintenance of neural circuits. Its expression in the brain and spinal cord suggests its involvement in neurological disorders and developmental abnormalities.
Research into CDH9 is essential for understanding its function in neuronal connectivity and potential implications in conditions such as autism, schizophrenia, and epilepsy.This CDH9 Polyclonal Antibody provides researchers with a valuable tool for studying the expression and localization of CDH9 in neural tissues, offering insights into its role in neurodevelopment and synaptic connectivity. Its specificity and sensitivity make it an ideal choice for investigations into the pathophysiology of neurological disorders and the development of potential therapeutic interventions targeting CDH9.
Product Name:
CDH9 Rabbit Polyclonal Antibody
SKU:
CAB14716
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 340-420 of human CDH9 (NP_057363.3).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
89kDa
Observed MW:
120kDa
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.
Purification Method:
Affinity purification
Gene ID:
1007
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDH9 Rabbit pAb (CAB14716) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
