null

CDH7 Antibody (PACO13719)

SKU:
PACO13719
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

CDH7 Antibody (PACO13719)

The CDH7 Polyclonal Antibody (PAC013719) is a valuable tool for researchers studying CDH7, a cell adhesion molecule involved in various physiological processes, particularly in the development of the nervous system. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications, enabling the detection and analysis of CDH7 protein expression in a variety of cell types.CDH7, also known as cadherin-7, plays a vital role in cell-cell adhesion and signaling pathways that are crucial for the formation and maintenance of neuronal circuits in the brain. Dysregulation of CDH7 expression has been linked to neurodevelopmental disorders and cognitive impairments, making it a focus of research in neuroscience and neurobiology.

By using the CDH7 Polyclonal Antibody, researchers can further elucidate the functions of CDH7 in neuronal development and synaptic plasticity, advancing our understanding of neurodevelopmental disorders and potentially leading to the development of novel therapies for neurological conditions. Its application in various research fields makes this antibody a valuable tool for investigations into the role of CDH7 in both normal and pathological conditions.

Antibody Name:CDH7 Antibody (PACO13719)
Antibody SKU:PACO13719
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human CDH7
Form:Liquid
Storage Buffer:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:cadherin 7, type 2;CDH7;CDH7L1 ;
UniProt Protein Function:CDH7: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
UniProt Protein Details:

Protein type:Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q22.1

Cellular Component: plasma membrane

NCBI Summary:This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in this gene may be associated with bipolar disease in human patients. This gene is present in a gene cluster on chromosome 18. [provided by RefSeq, May 2016]
UniProt Code:Q9ULB5
NCBI GenInfo Identifier:296434420
NCBI Gene ID:1005
NCBI Accession:Q9ULB5.2
UniProt Secondary Accession:Q9ULB5,Q9H157,
UniProt Related Accession:Q9ULB5
Molecular Weight:87,086 Da
NCBI Full Name:Cadherin-7
NCBI Synonym Full Names:cadherin 7
NCBI Official Symbol:CDH7  
NCBI Official Synonym Symbols:CDH7L1  
NCBI Protein Information:cadherin-7
UniProt Protein Name:Cadherin-7
Protein Family:Cadherin
UniProt Gene Name:CDH7  
UniProt Entry Name:CADH7_HUMAN

Related Products