CDH7 Antibody (PACO00499)
- SKU:
- PACO00499
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
CDH7 Antibody (PACO00499)
The CDH7 Antibody (PACO00499) is a valuable tool for research involving the CDH7 protein, also known as Cadherin-7. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the CDH7 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in developmental biology, neuroscience, and cancer research.CDH7 is a cell adhesion molecule that plays a crucial role in cell-cell adhesion and signaling processes, particularly in the development of tissues and organs. Its involvement in various cellular functions makes it an important target for studying developmental processes, neuronal growth, and tumor progression.
By understanding the function and regulation of CDH7, researchers can gain insights into potential therapeutic strategies for conditions related to abnormal cell adhesion and signaling pathways.In conclusion, the CDH7 Antibody (PACO00499) offers researchers a reliable tool for studying the role of CDH7 in various biological processes, providing valuable insights into development, neuronal function, and cancer biology. Its specificity and reactivity make it a valuable asset for experimental investigations aimed at understanding the mechanisms underlying disease progression and tissue development.
| Antibody Name: | CDH7 Antibody |
| Antibody SKU: | PACO00499 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the C-terminal region of human Cadherin-7. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | CDH7; CDH7L1; Cadherin-7 |
| UniProt Protein Function: | CDH7: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 18q22.1 Cellular Component: plasma membrane |
| NCBI Summary: | This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in this gene may be associated with bipolar disease in human patients. This gene is present in a gene cluster on chromosome 18. [provided by RefSeq, May 2016] |
| UniProt Code: | Q9ULB5 |
| NCBI GenInfo Identifier: | 296434420 |
| NCBI Gene ID: | 1005 |
| NCBI Accession: | Q9ULB5.2 |
| UniProt Secondary Accession: | Q9ULB5,Q9H157, |
| UniProt Related Accession: | Q9ULB5 |
| Molecular Weight: | 87,086 Da |
| NCBI Full Name: | Cadherin-7 |
| NCBI Synonym Full Names: | cadherin 7 |
| NCBI Official Symbol: | CDH7Â Â |
| NCBI Official Synonym Symbols: | CDH7L1Â Â |
| NCBI Protein Information: | cadherin-7 |
| UniProt Protein Name: | Cadherin-7 |
| Protein Family: | Cadherin |
| UniProt Gene Name: | CDH7Â Â |
| UniProt Entry Name: | CADH7_HUMAN |
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