CDH5 Rabbit Polyclonal Antibody (CAB12416)
- SKU:
- CAB12416
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CDH5 Rabbit Polyclonal Antibody |
SKU: | CAB12416 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 621-784 of human VE Cadherin (NP_001786.2). |
Sequence: | RRRL RKQA RAHG KSVP EIHE QLVT YDEE GGGE MDTT SYDV SVLN SVRR GGAK PPRP ALDA RPSL YAQV QKPP RHAP GAHG GPGE MAAM IEVK KDEA DHDG DGPP YDTL HIYG YEGS ESIA ESLS SLGT DSSD SDVD YDFL NDWG PRFK MLAE LYGS DPRE ELLY |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | 7B4; CD144; VE Cadherin |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 88kDa |
Observed MW: | 140kDa |
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
Purification Method: | Affinity purification |
Gene ID: | 1003 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |