VE Cadherin Rabbit Polyclonal Antibody (CAB0734)
- SKU:
- CAB0734
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | VE Cadherin Rabbit Polyclonal Antibody |
SKU: | CAB0734 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 259-358 of human VE Cadherin (NP_001786.2). |
Sequence: | TQTK YTFV VPED TRVG TSVG SLFV EDPD EPQN RMTK YSIL RGDY QDAF TIET NPAH NEGI IKPM KPLD YEYI QQYS FIVE ATDP TIDL RYMS PPAG NRAQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | 7B4; CD144; VE Cadherin |
Positive Sample: | HUVEC,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 88kDa |
Observed MW: | 130kDa |
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
Purification Method: | Affinity purification |
Gene ID: | 1003 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |