CDH3 Rabbit Polyclonal Antibody (CAB14235)
- SKU:
- CAB14235
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | CDH3 Rabbit Polyclonal Antibody |
SKU: | CAB14235 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-350 of human CDH3 (NP_001784.2). |
Sequence: | SEPC RAVF REAE VTLE AGGA EQEP GQAL GKVF MGCP GQEP ALFS TDND DFTV RNGE TVQE RRSL KERN PLKI FPSK RILR RHKR DWVV APIS VPEN GKGP FPQR LNQL KSNK DRDT KIFY SITG PGAD SPPE GVFA VEKE TGWL LLNK PLDR EEIA KYEL FGHA VSEN GASV EDPM NISI IVTD QNDH KPKF TQDT FRGS VLEG VLPG TSVM QVTA TDED DAIY TYNG VVAY SIHS QEPK DPHD LMFT IHRS TGTI SVIS SGLD REKV PEYT LTIQ ATDM DGDG STTT AVAV VEIL DAND NAPM FDPQ KYEA HVPE NAVG HEVQ RLT |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CDHP; HJMD; PCAD; CDH3 |
Positive Sample: | Mouse brain,Rat testis,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 91kDa |
Observed MW: | 115kDa |
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).
Purification Method: | Affinity purification |
Gene ID: | 1001 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |