The CDH26 Polyclonal Antibody (PACO37878) is a key tool for researchers investigating the role of CDH26, a cell adhesion molecule with implications in various biological processes. Raised in rabbits, this antibody demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the CDH26 protein, this antibody enables precise detection and analysis in a wide range of cell types, making it an ideal tool for studies in cell biology, developmental biology, and cancer research.CDH26, also known as cadherin-26, is a critical player in cell-cell adhesion and tissue organization, contributing to processes such as embryogenesis and wound healing.
Its involvement in these fundamental processes underscores its importance as a target for research into developmental disorders, cancer metastasis, and tissue repair mechanisms. By elucidating the functions of CDH26, researchers can gain valuable insights into the underlying mechanisms of various physiological and pathological conditions, potentially leading to the development of novel therapeutic strategies.
Antibody Name:
CDH26 Antibody (PACO37878)
Antibody SKU:
PACO37878
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Cadherin-like protein 26 protein (1-124AA)
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Synonyms:
Cadherin-like protein 26 (Cadherin-like protein VR20), CDH26
UniProt Protein Function:
CDH26: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 20q13.33Cellular Component: integral to membrane; plasma membraneMolecular Function: calcium ion bindingBiological Process: homophilic cell adhesion
UniProt Protein Details:
NCBI Summary:
Cadherins are a family of adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization and migration. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This gene encodes a cadherin domain-containing protein whose specific function has not yet been determined. Alternative splicing occurs at this locus and two transcript variants, encoding distinct proteins, have been identified. [provided by RefSeq, Jul 2008]
