UniProt Protein Function: | CDH22: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues.Protein type: Cell adhesion; Membrane protein, integralChromosomal Location of Human Ortholog: 20q13.1Cellular Component: integral to membrane; plasma membraneMolecular Function: calcium ion bindingBiological Process: calcium-dependent cell-cell adhesion; homophilic cell adhesion |
UniProt Protein Details: | |
NCBI Summary: | This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UJ99 |
NCBI GenInfo Identifier: | 24211543 |
NCBI Gene ID: | 64405 |
NCBI Accession: | Q9UJ99.2 |
UniProt Secondary Accession: | Q9UJ99,O43205, B9EGK7 |
UniProt Related Accession: | Q9UJ99 |
Molecular Weight: | 89,091 Da |
NCBI Full Name: | Cadherin-22 |
NCBI Synonym Full Names: | cadherin 22 |
NCBI Official Symbol: | CDH22Â Â |
NCBI Official Synonym Symbols: | C20orf25; dJ998H6.1Â Â |
NCBI Protein Information: | cadherin-22 |
UniProt Protein Name: | Cadherin-22 |
UniProt Synonym Protein Names: | Pituitary and brain cadherin; PB-cadherin |
Protein Family: | Cadherin |
UniProt Gene Name: | CDH22Â Â |
UniProt Entry Name: | CAD22_HUMAN |