UniProt Protein Function: | CDH20: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 18q21.33 |
UniProt Protein Details: | |
NCBI Summary: | This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9HBT6 |
NCBI GenInfo Identifier: | 190359622 |
NCBI Gene ID: | 28316 |
NCBI Accession: | Q9HBT6.2 |
UniProt Secondary Accession: | Q9HBT6,Q495S3 |
UniProt Related Accession: | Q9HBT6 |
Molecular Weight: | 88,993 Da |
NCBI Full Name: | Cadherin-20 |
NCBI Synonym Full Names: | cadherin 20 |
NCBI Official Symbol: | CDH20Â Â |
NCBI Official Synonym Symbols: | Cdh7; CDH7L3Â Â |
NCBI Protein Information: | cadherin-20 |
UniProt Protein Name: | Cadherin-20 |
UniProt Synonym Protein Names: | |
Protein Family: | Cadherin |
UniProt Gene Name: | CDH20Â Â |
UniProt Entry Name: | CAD20_HUMAN |