The CDH20 Polyclonal Antibody (PAC003916) is a valuable tool for researchers studying CDH20, a cell adhesion molecule that plays a key role in cellular communication and tissue development. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications.CDH20 is involved in cell-to-cell adhesion and is particularly important in the formation and maintenance of neural connections in the brain. Dysfunction of CDH20 has been implicated in various neurological disorders, making it an interesting target for research in neuroscience and developmental biology.
By binding specifically to CDH20, this antibody allows for the detection and analysis of CDH20 protein expression in different cell types, providing valuable insights into its function. Researchers in fields such as neurobiology, cell biology, and genetics will find this antibody useful for their studies on cell adhesion and neuronal development.Overall, the CDH20 Polyclonal Antibody is a reliable tool for investigating the role of CDH20 in cellular processes and development, and it has the potential to contribute to advancements in understanding neurological diseases and disorders.
Antibody Name:
CDH20 Antibody
Antibody SKU:
PACO03916
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC, IF
Recommended Dilutions:
IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the Internal region of human Cadherin-20.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
CDH20; CDH7L3; Cadherin-20
UniProt Protein Function:
CDH20: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 18q21.33
UniProt Protein Details:
NCBI Summary:
This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008]
