CDH11 Rabbit Polyclonal Antibody (CAB12176)
- SKU:
- CAB12176
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CDH11 Rabbit Polyclonal Antibody |
SKU: | CAB12176 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human CDH11 (NP_001788.2). |
Sequence: | ERAQ YTLM AQAV DRDT NRPL EPPS EFIV KVQD INDN PPEF LHET YHAN VPER SNVG TSVI QVTA SDAD DPTY GNSA KLVY SILE GQPY FSVE AQTG IIRT ALPN MDRE AKEE YHVV IQAK DMGG HMGG LSGT TKVT ITLT DVND NPPK FPQS VYQM SVSE AAVP GEEV GRVK AKDP DIGE NGLV TYNI VDGD GMES FEIT TDYE TQEG VIKL KKPV DFET KRAY SLKV EAAN VHID PKFI SNGP FKDT VTVK ISVE DADE PPMF LAPS YIHE VQEN AAAG T |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | OB; ESWS; CAD11; CDHOB; OSF-4; TBHS2; CDH11 |
Positive Sample: | U-87MG,A-549,HT-29 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 88kDa |
Observed MW: | 110kDa |
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
Purification Method: | Affinity purification |
Gene ID: | 1009 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |