The CDCA8 Polyclonal Antibody (CAB12594) is a crucial tool for researchers studying CDCA8, a protein involved in cell division and DNA replication. This antibody, produced in rabbits, exhibits a high level of reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CDCA8 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in cancer research and molecular biology.CDCA8, also known as Borealin, plays a vital role in ensuring the proper segregation of chromosomes during cell division, making it a key player in maintaining genomic stability.
Dysregulation of CDCA8 has been linked to various types of cancer, making it a promising target for therapeutic intervention. By understanding the function and regulation of CDCA8, researchers can gain valuable insights into the mechanisms underlying cancer progression and potentially develop novel treatment strategies.
Product Name:
CDCA8 Rabbit Polyclonal Antibody
SKU:
CAB12594
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human CDCA8 (NP_060571.1).
This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16.
Purification Method:
Affinity purification
Gene ID:
55143
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse testis, using CDCA8 Rabbit pAb (CAB12594) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
