Cdc6 Rabbit Polyclonal Antibody (CAB18249)
- SKU:
- CAB18249
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | Cdc6 Rabbit Polyclonal Antibody |
SKU: | CAB18249 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-560 of human Cdc6 (Q99741). |
Sequence: | MPQT RSQA QATI SFPK RKLS RALN KAKN SSDA KLEP TNVQ TVTC SPRV KALP LSPR KRLG DDNL CNTP HLPP CSPP KQGK KENG PPHS HTLK GRRL VFDN QLTI KSPS KREL AKVH QNKI LSSV RKSQ EITT NSEQ RCPL KKES ACVR LFKQ EGTC YQQA KLVL NTAV PDRL PARE REMD VIRN FLRE HICG KKAG SLYL SGAP GTGK TACL SRIL QDLK KELK GFKT IMLN CMSL RTAQ AVFP AIAQ EICQ EEVS RPAG KDMM RKLE KHMT AEKG PMIV LVLD EMDQ LDSK GQDV LYTL FEWP WLSN SHLV LIGI ANTL DLTD RILP RLQA REKC KPQL LNFP PYTR NQIV TILQ DRLN QVSR DQVL DNAA VQFC ARKV SAVS GDVR KALD VCRR AIEI VESD VKSQ TILK PLSE CKSP SEPL IPKR VGLI HISQ VISE VDGN RMTL SQEG AQDS FPLQ QKIL VCSL MLLI RQLK IKEV TLGK LYEA YSKV CRKQ QVAA VDQS ECLS LSGL LEAR GILG LKRN KETR LTKV FFKI EEKE IEHA LKDK ALIG NILA TGLP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CDC18L; HsCDC6; MGORS5; HsCDC18; Cdc6 |
Positive Sample: | HeLa |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 63kDa |
Observed MW: | 62kDa |
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
Purification Method: | Affinity purification |
Gene ID: | 990 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |