The CDC34 Polyclonal Antibody (CAB5457) is a valuable tool for researchers studying CDC34, a crucial protein involved in the ubiquitin-proteasome pathway. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the CDC34 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology, cell signaling, and cancer research.CDC34 is a key player in the ubiquitination process, facilitating the tagging of proteins for degradation and regulating various cellular processes such as cell cycle progression and DNA repair.
Dysregulation of CDC34 has been linked to the development of cancer and other diseases, making it an attractive target for therapeutic interventions. By investigating the function and regulation of CDC34, researchers can gain valuable insights into the underlying mechanisms of disease pathogenesis and potentially identify novel treatment strategies.
Product Name:
CDC34 Rabbit Polyclonal Antibody
SKU:
CAB5457
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-236 of human CDC34 (NP_004350.1).
The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication.
Purification Method:
Affinity purification
Gene ID:
997
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse testis, using CDC34 antibody (CAB5457) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
