The CDC25C Polyclonal Antibody (CAB1672) is a valuable tool for researchers studying cell division cycle 25C (CDC25C), a key regulator of cell cycle progression. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards CDC25C protein in human samples, making it an ideal choice for Western blot applications.CDC25C, a phosphatase enzyme, plays a crucial role in promoting cell division by activating cyclin-dependent kinases. Dysregulation of CDC25C has been associated with various diseases, including cancer, making it a promising target for therapeutic interventions.
By utilizing the CAB1672 antibody, researchers can study CDC25C expression levels and activity in different cell types, aiding in the advancement of cancer research and drug development efforts.Overall, the CDC25C Polyclonal Antibody (CAB1672) holds great potential for deepening our understanding of cell cycle regulation and its implications in disease pathogenesis. Its efficacy in detecting CDC25C protein makes it a valuable asset for researchers seeking to unravel the complexities of cell division processes.
Product Name:
CDC25C Rabbit Polyclonal Antibody
SKU:
CAB1672
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-130 of human CDC25C (NP_001781.2).
This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described.
Purification Method:
Affinity purification
Gene ID:
995
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CDC25C antibody (CAB1672) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
