CDC23 Rabbit Polyclonal Antibody (CAB15116)
- SKU:
- CAB15116
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CDC23 Rabbit Polyclonal Antibody |
SKU: | CAB15116 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CDC23 (NP_004652.2). |
Sequence: | HSSK WSAE LAFS LPAL PLAE LQPP PPIT EEDA QDMD AYTL AKAY FDVK EYDR AAHF LHGC NSKK AYFL YMYS RYLS GEKK KDDE TVDS LGPL EKGQ VKNE A |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:200 |
Synonyms: | APC8; CUT23; ANAPC8; CDC23 |
Positive Sample: | U-87MG,293T,HeLa,Jurkat,HepG2,NIH/3T3,mouse liver,mouse kidney,rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleoplasm |
Calculated MW: | 69kDa |
Observed MW: | 69kDa |
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
Purification Method: | Affinity purification |
Gene ID: | 8697 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |