The CDC20 Polyclonal Antibody (CAB15656) is a valuable tool for researchers studying CDC20, a key regulator of cell division and checkpoint control. This antibody, produced in rabbits, is highly specific for CDC20 and is validated for use in Western blot applications. By binding to the CDC20 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in cell biology and cancer research.CDC20 is essential for proper cell cycle progression, as it coordinates the separation of sister chromatids during mitosis. Dysregulation of CDC20 has been linked to chromosomal instability and tumorigenesis, making it a promising target for cancer therapy.
By understanding the role of CDC20 in cellular processes, researchers can develop targeted therapies to combat cancer and other diseases characterized by abnormal cell division.Overall, the CDC20 Polyclonal Antibody is a valuable asset for researchers investigating the role of CDC20 in cell division and disease development. Its high specificity and sensitivity make it a reliable tool for studying the function of CDC20 in various biological contexts.
Product Name:
CDC20 Rabbit Polyclonal Antibody
SKU:
CAB15656
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CDC20 (NP_001246.2?).
Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, spindle pole.
Calculated MW:
55kDa
Observed MW:
55kDa
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.
Purification Method:
Affinity purification
Gene ID:
991
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from PC-3 cells, using CDC20 Rabbit pAb (CAB15656) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
