The CDC20 Polyclonal Antibody (CAB1231) is a valuable tool for research involving CDC20, a protein known for its role in cell cycle regulation. The antibody is raised in rabbits and has high reactivity with human samples, making it a reliable tool for Western blot applications. By binding to the CDC20 protein, this antibody enables the detection and analysis of CDC20 in various cell types, making it suitable for studies in cell biology and cancer research.CDC20 is a key player in the cell cycle, specifically in the regulation of cell division and chromosome segregation.
Dysregulation of CDC20 has been implicated in various diseases, including cancer, making it an important target for research in understanding the mechanisms of tumorigenesis and potential therapeutic interventions. By studying the activity of CDC20, researchers can gain valuable insights into the molecular processes underlying cell cycle progression and identify new strategies for combating cancer and other related diseases.
Product Name:
CDC20 Rabbit Polyclonal Antibody
SKU:
CAB1231
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CDC20 (NP_001246.2).
Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, spindle pole.
Calculated MW:
55kDa
Observed MW:
55kDa
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.
Purification Method:
Affinity purification
Gene ID:
991
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CDC20 antibody (CAB1231) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
