CDC16 Rabbit Polyclonal Antibody (CAB7197)
- SKU:
- CAB7197
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CDC16 Rabbit Polyclonal Antibody |
SKU: | CAB7197 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 371-620 of human CDC16 (NP_003894.3). |
Sequence: | MLYI GLEY GLTN NSKL AERF FSQA LSIA PEDP FVMH EVGV VAFQ NGEW KTAE KWFL DALE KIKA IGNE VTVD KWEP LLNN LGHV CRKL KKYA EALD YHRQ ALVL IPQN ASTY SAIG YIHS LMGN FENA VDYF HTAL GLRR DDTF SVTM LGHC IEMY IGDS EAYI GADI KDKL KCYD FDVH TMKT LKNI ISPP WDFR EFEV EKQT AEET GLTP LETS RKTP DSRP SLEE TFEI EMNE SDMM LETS MSDH ST |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | APC6; CUT9; ANAPC6; CDC16Hs; CDC16 |
Positive Sample: | Jurkat,HepG2,HeLa,A-549,Mouse brain,Mouse ovary,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, spindle. |
Calculated MW: | 72kDa |
Observed MW: | 72kDa |
The protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR) domain; a protein domain that is often involved in protein-protein interactions and the assembly of multiprotein complexes. Multiple alternatively spliced transcript variants, encoding distinct proteins, have been identified.
Purification Method: | Affinity purification |
Gene ID: | 8881 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |