The CDA Polyclonal Antibody (CAB13959) is a valuable tool for researchers studying the CD300A protein, an important cell surface molecule involved in immune regulation. This antibody, derived from rabbit serum, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CD300A protein, this antibody enables researchers to detect and analyze CD300A in various cell types, making it ideal for studies in immunology and cancer research.CD300A, also known as an immune inhibitory receptor, plays a crucial role in maintaining immune homeostasis by regulating inflammation and inhibiting allergic reactions.
Its role in immune response modulation makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By understanding the function of CD300A, researchers can develop therapies that manipulate or enhance immune function in these disease contexts. The CDA Polyclonal Antibody (CAB13959) provides a reliable tool for studying CD300A and advancing our understanding of immune regulation in health and disease.
Product Name:
CDA Rabbit Polyclonal Antibody
SKU:
CAB13959
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human CDA (NP_001776.1).
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
Purification Method:
Affinity purification
Gene ID:
978
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CDA Rabbit pAb (CAB13959) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
