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CD99R monoclonal antibody (FITC) (AGIM0071)

SKU:
AGIM0071
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgM
Clone:
MEM-131
Conjugation:
FITC
Applications:
FC
€179
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Description

system_update_altDatasheet
Product Name:CD99R monoclonal antibody (FITC)
Product Code:AGIM0071
Size:500 µL
Reactivity:Human
Clone:MEM-131
Applications:Flow Cytometry
Conjugate:FITC
Isotype:IgM
Host Species:Mouse
Storage:Store at 4°C. Avoid prolonged exposure to light.
Uniprot:P14209
Background:CD99 (E2, MIC2) is a transmembrane glycoprotein that is involved in regulation of T cell addhesive properties and programmed cell death distinct from typical apoptosis course. CD99 roles are specific to certain stages of T cell differentiation such as corticothymocytes. CD99R isoform expression is restricted in the haematopoietic system to T, NK and myeloid cells.
UniProt Protein Function:Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes.
NCBI Summary:The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016]
UniProt Code:P14209
NCBI GenInfo Identifier:119049
NCBI Gene ID:4267
NCBI Accession:P14209.1
UniProt Secondary Accession:P14209,O00518, Q6ICV7, A6NIW1,
UniProt Related Accession:P14209
Molecular Weight:17,128 Da
NCBI Full Name:CD99 antigen
NCBI Synonym Full Names:CD99 molecule (Xg blood group)
NCBI Official Symbol:CD99  
NCBI Official Synonym Symbols:MIC2; HBA71; MIC2X; MIC2Y; MSK5X  
NCBI Protein Information:CD99 antigen
UniProt Protein Name:CD99 antigen
UniProt Synonym Protein Names:12E7; E2 antigen; Protein MIC2; T-cell surface glycoprotein E2; CD_antigen: CD99
Protein Family:CD99 antigen
UniProt Gene Name:CD99  

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