CD97 Rabbit Polyclonal Antibody (CAB3780)
- SKU:
- CAB3780
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | CD97 Rabbit Polyclonal Antibody |
SKU: | CAB3780 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-435 of human CD97 (NP_001775.2). |
Sequence: | NLED IMRI LAKS LPKG PFTY ISPS NTEL TLMI QERG DKNV TMGQ SSAR MKLN WAVA AGAE DPGP AVAG ILSI QNMT TLLA NASL NLHS KKQA ELEE IYES SIRG VQLR RLSA VNSI FLSH NNTK ELNS PILF AFSH LESS DGEA GRDP PAKD VMPG PRQE LLCA FWKS DSDR GGHW ATEG CQVL GSKN GSTT CQCS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | CD97; TM7LN1 |
Positive Sample: | HepG2,Jurkat,Mouse lung,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein, Secreted, extracellular space. |
Calculated MW: | 92kDa |
Observed MW: | 105kDa |
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.
Purification Method: | Affinity purification |
Gene ID: | 976 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |