The CD97 Antigen Polyclonal Antibody (CAB3780) is a valuable tool for researchers studying the CD97 antigen, a cell surface receptor involved in various cellular processes. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CD97 antigen, this antibody allows for the detection and analysis of this protein in different cell types, making it ideal for studies in immunology, cancer research, and beyond.The CD97 antigen is known to play a role in cell adhesion, migration, and signal transduction, making it a key player in processes such as inflammation, tumor metastasis, and immune cell interaction.
Research on the CD97 antigen has implications for understanding diseases such as cancer, autoimmune disorders, and inflammatory conditions, and may lead to the development of targeted therapies.By utilizing the CD97 Antigen Polyclonal Antibody (CAB3780), researchers can gain valuable insights into the function and regulation of the CD97 antigen, paving the way for advancements in various fields of biomedical research.
Product Name:
CD97 Rabbit Polyclonal Antibody
SKU:
CAB3780
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-435 of human CD97 (NP_001775.2).
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.
Purification Method:
Affinity purification
Gene ID:
976
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CD97 antibody (CAB3780) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
