CD8B Rabbit Polyclonal Antibody (CAB3286)
- SKU:
- CAB3286
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
Product Name: | CD8B Rabbit Polyclonal Antibody |
SKU: | CAB3286 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-170 of human CD8B (NP_757362.1). |
Sequence: | LQQT PAYI KVQT NKMV MLSC EAKI SLSN MRIY WLRQ RQAP SSDS HHEF LALW DSAK GTIH GEEV EQEK IAVF RDAS RFIL NLTS VKPE DSGI YFCM IVGS PELT FGKG TQLS VVDF LPTT AQPT KKST LKKR VCRL PRPE TQKG PLCS P |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LY3; P37; LEU2; LYT3; Ly-3; CD8B1; CD8beta; CD8B |
Positive Sample: | 293F transfected with CD8B |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein, Single-pass type I membrane protein. |
Calculated MW: | 24kDa |
Observed MW: | 23kDa |
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Purification Method: | Affinity purification |
Gene ID: | 926 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |