CD8A Rabbit Monoclonal Antibody (CAB0663)
- SKU:
- CAB0663
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | CD8A Rabbit Monoclonal Antibody |
SKU: | CAB0663 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 136-235 of human CD8A (P01732). |
Sequence: | KPTT TPAP RPPT PAPT IASQ PLSL RPEA CRPA AGGA VHTR GLDF ACDI YIWA PLAG TCGV LLLS LVIT LYCN HRNR RRVC KCPR PVVK SGDK PSLS ARYV |
Tested Applications: | WB FC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 FC,1:50 - 1:200 |
Synonyms: | CD8; p32; Leu2; CD8alpha; CD8A |
Positive Sample: | PC-3 cells,THP-1 cells |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein |
Calculated MW: | 26kDa |
Observed MW: | 35kDa |
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein.
Purification Method: | Affinity purification |
Gene ID: | 925 |
Clone Number: | ARC0329 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |