The CD8a Polyclonal Antibody (CAB10007) is a valuable tool for researchers studying the CD8a protein, a co-receptor found on the surface of cytotoxic T cells. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it suitable for use in Western blot applications. By targeting the CD8a protein, this antibody facilitates the detection and analysis of CD8a expression in various cell types, making it an essential component in studies related to immunology and cancer research.
CD8a is a crucial component of the adaptive immune response, aiding in the identification and elimination of infected or malignant cells by cytotoxic T cells. Its role in immune surveillance and activation makes it a significant target for research into diseases such as cancer and viral infections. Understanding the function and regulation of CD8a is essential in developing novel therapies that leverage the immune system to combat these conditions.
Product Name:
CD8A Polyclonal Antibody
SKU:
CAB22114
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant protein of mouse CD8A
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
Ly-2; Ly-B; Ly-35; Lyt-2; CD8A
Positive Sample:
Mouse spleen,RAW 264.7
Conjugate:
Unconjugated
Cellular Localization:
cell surface, external side of plasma membrane, plasma membrane, plasma membrane raft
Calculated MW:
27kDa
Observed MW:
35-42kDa
Enables identical protein binding activity. Acts upstream of or within several processes, including cytotoxic T cell differentiation; defense response to virus; and positive regulation of calcium-mediated signaling. Located in external side of plasma membrane. Is expressed in several structures, including endocrine gland; exocrine gland; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human CD8A (CD8a molecule).
Purification Method:
Affinity purification
Gene ID:
12525
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CD8A Rabbit pAb (CAB22114) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
